Medical Essay Example | Topics and Well Written Essays - 500 words

Clinical - Essay Example She likewise detailed troublesomely in talking bringing about somewhat slurred discourse. Her sister likewise remarked on her facial appearance saying that her face appeared to be deformed. While eating she likewise saw having extreme tearing in the correct eye (Crocodile tears). These side effects logically exacerbated through the span of the following 8 hours and in this way she chose to experience assessment for these protests. She doesn't have some other existing comorbid conditions and has not had any comparative grumblings previously. Her past clinical history uncovered that she had as of late recouped from a scene of regular cold and her family ancestry was certain for diabetes, in any case, she herself is anything but a known diabetic. Social history was unremarkable. Physical Examination: On assessment of the face, it was seen that the nasolabial overlays on the left half of the face were leveled and the patient couldn't totally close her left eye. At the point when the pati ent was asked to mightily close her correct eye, internal and upward moving of the eyeball was noted, for example exhibition of the Bell’s wonder (Monnell and Zachariah, 2009). At the point when she was approached to cause a commotion and grin, shortcoming of the correct facial muscles was noted.

The Consumption Function Essay Example for Free

The Consumption Function Essay To make the pay use model increasingly practical, we should present different parts of interest, including the legislature and the remote segment. In any case, first we have to perceive that purchasers arranged uses will rely upon their degree of salary. †¢Consumer Spending and Income The utilization work portrays the connection between wanted spending by buyers and the degree of salary. At the point when buyers have more pay, they will need to buy more merchandise and enterprises. A basic utilization capacity can be depicted by the condition C = Ca + by In which all out utilization spending, C, has two sections. The initial segment, Ca, is called independent utilization, and it doesn't straightforwardly rely upon the degree of pay. The subsequent part, by, speaks to the piece of utilization that depends on salary. It is the result of the portion b, called the minor penchant to expend (MPC), and level of salary in the economy, y. The MPC, which has an estimation of b in our recipe, discloses to us how much utilization spending will increment for each dollar that pay increments. In the event that b approaches 0.7, at that point for each $1 that salary builds, utilization would increment by 0.7 ÃŽ § $1, or $0.70. As firms produce yield, they pay families pay as wages, intrigue, benefits, and leases. We can along these lines use y to speak to both yield and salary. †¢Changes in the Consumption Function The utilization work is dictated by the degree of self-governing utilization and by the MPC. The degree of self-governing utilization can change, thus can the MPC. Changes in either move the utilization capacity to another situation on the chart. A more significant level of self-governing utilization however no change in MPC will move the whole utilization work upward and corresponding to its unique position. More utilization happens at each degree of salary. Various components can make independent utilization change. Here are two: Increments in buyer riches will cause an expansion in self-governing utilization. Riches comprises of the estimation of stocks, bonds, and purchaser durables (buyer merchandise that keep going quite a while, for example, autos and fridges). Note that a person’s riches isn't equivalent to pay. Pay is the measure of cash somebody procures during a period, for example, in a given year, while riches speaks to the people all out total assets. Increments in purchaser certainty will increment self-governing utilization proportion. Forecasters focus on customer certainty, a measure dependent on family studies of how positive purchasers are feeling about the future, since it encourages them to anticipate utilization spending. The Conference Board, a not-for-profit association committed to spreading monetary examination, distributes a list of buyer certainty every month that numerous forecasters depend on. An adjustment in the peripheral inclination to devour will cause an adjustment in the slant of the utilization work.

Out for the Holidays - UGA Undergraduate Admissions

Out for the Holidays - UGA Undergraduate Admissions Out for the Holidays Our office will be closed for the Holiday break, and we will not return until early January. As such, any emails, mailings, phone calls, etc. will not be acted upon until after the holiday break. As well, I will only be making sporadic checks on the blog posts, so please be patient. As well, when we return in January, we will be working for a few days on enrolling Spring students and then right into freshman application deadline issues, so any questions that can wait (summer/fall transfer issues, questions about HS juniors or younger, etc.) should be put on hold until later in January. Go Dawgs!

Biomedical Ethics - Free Essay Example

Sample details Pages: 1 Words: 320 Downloads: 10 Date added: 2019/10/10 Did you like this example? In every advanced democratic industry, there exists a right to health care. This is because the whole population has the right to provide public health protection where there is a risk of injury, the disease as well as life security on medical issues. There is institution that is put in place to provide the assurance for the people who don’t have money to pay for it. The poor and middle-class people in the United State have no life insurance cover but the state provides them the right to emergencies services. Other developing countries gives right for health care by creating policies which do not necessarily meet the health care to be fully a need in the population. There are variety of health care systems that embodied the regal right for health care (Manning et al, 2007). This ranges from government providing health care services and providing national health services. There is a great different type of legal right where the degree the insurance covers the person varies from type of mental health reproductive technologies, and long term services care. Don’t waste time! Our writers will create an original "Biomedical Ethics" essay for you Create order There are positive and negative rights that are given as medical care’s where the positive right requires a favor to the right bearer while the negative right requires a refrain from doing something harmful to the right bearer (Manning et al, 2007). This is given for instance that a person requires going beyond what is allocated but he feels that he can go past that to get his right of doing it. On refrain, the access to the health right should be given equally to all people without determining what one have. The nation tried to change the health care system and make sure that all citizens are having an access to affordable health insurance. Healthcare important contribution protects the open opportunities for individuals for it protect the normal functioning of every individual and make all people equal competitors and cooperators.

The Death Penalty Act Of 1851 Essay - 1724 Words

Legal executions in Californian were authorized under the criminal practice act of 1851 and later lead capital punishment to be incorporated into the penal code on Feb. 14, 1872. Essentially, hanging was allowed to be implemented and caused executions to be publicized. In 1937, legislature allowed lethal gas which effectively replaced hanging and lead to the building of the only lethal gas chamber in the state of California at San Quentin. The first execution by lethal gas was conducted in 1938 and the continued use of lethal gas lasted through 1967. A total of 194 people were executed by lethal gas, all at San Quentin and included the execution of four women. Twenty-five years after 1967, the number of executions in California halted due to various state and United States Supreme Court decisions, effectively allowed the death penalty to be reviewed. In 2014 the California Supreme Court found that the death penalty constituted cruel and unusual punishment under the state constitution. Although the state of California constituted the death penalty as a cruel punishment, other states have made it a point to continuously use public executions and have used different forms of the death penalty. Arthur Miller, an American playwright, wrote an essay satirizing public executions in 1992. The essay name â€Å"Get it Right. Privatize Executions† revealed Miller’s argument of making executions into live entertainment. Clearly, Miller wanted to satirize the way Americans have takenShow MoreRelatedEssay about The High Cost of Capital Punishment855 Words   |  4 Pagesconvicted criminals to serve less than fifty percent of their sentence because the state simply can’t afford to keep them behind bars any longer. These same states are sinking millions of dollars into the death penalty every year. It has been shown in many cases that the cost of a death penalty case is much greater than that of a life without parole case. One such case comes out of a study that was done in Colorado that concluded that capital proceedings on average require one hundred and twentyRead MoreThe Debate Of Capital Punishment1313 Words   |  6 PagesCapital Punishment Introduction The state of California has carried out 13 executions since the enactment of capital punishment in 1992 (NAACP, 2016, 10). According to the NAACP winter quarterly report, there are currently 743 prisoners on death row (NAACP, 2016, 39). Since the enactment, there has been a wide range of political debate. The largest concern is in regards to the number of wrongful convictions and its philosophical underpinnings. The citizens in California are as diverse as theirRead MoreThe Punishment Of The Death Penalty1620 Words   |  7 Pagesdeclared that the crimes committed by people under the age of 18 would not be punishable by death. Because of this the United States Supreme Court challenged the constitutionality of the death penalty for juveniles. Whether the decision was appropriate or not is still under intense debate to this day. â€Å"A primary purpose of the juvenile justice system is to hold juvenile offenders accountable for delinquent acts while providing treatment, rehabilitat ive services, and programs designed to prevent futureRead MoreDeath Penalty Is Cruel And Unusual Punishment1706 Words   |  7 PagesThe legal executions first started in California when it was under the Practices Act in 1851. Then in February 14th 1872 it was put in the Penal Code. Capital punish in counties continued until an amendment by the legislature in 1891 said that it could only happen in the State Prisons picked by the court. The first state execution in California happens on March 3rd 1893 at San Quentin and the first one in Folsom was on December 13th 1895. In the 1937’s the legislature decided that instead of hangingRead MoreThe Legal Issues and Ethical Effects of the Deepwater Horizon Explosion and British Petroleum Oil Spill in the Gulf of Mexico 20101542 Words   |  7 Pagesand the subsequent oil spill into the Gulf of Mexico. There are many legal issues surrounding this disaster, but the three this paper will focus on are the Oil Pollution Act of 1990, m aritime laws, and criminal charges that may be brought against BP executives. The ethical issues explored will be who is responsible for deaths due to the Deepwater Horizon explosion, who is responsible for the oil cleanup, and who is required to compensate the people whose livelihood has been put in jeopardy. Read MoreIs Capital Punishment Constitutional?2107 Words   |  9 PagesThe United States of America, and nations worldwide mourned the execution of Troy Anthony Davis on September 22 of 2011. He was a convicted felon sentenced to death for the murder of a police officer in the state of Georgia. Davis became the face of capital punishment before and after his execution, causing uproar from the public and public figures worldwide. In an interview for CNN, Germany’s junior minister for human rights, Marcus Loening, stated, â€Å"There are still serious doubts about his guiltRead MoreAnalysis Of Mary Shelley s Frankenstein 1402 Words   |  6 PagesOne of the greatest pieces of literature during the Romantic Period is the novel, Frankenstein. This intelligent work of art was written by Mary Shelley. Shelley was born in London on August 30th, 1797 and died on February 1, 1851. People from all around the world have heard about the monster created by the one and only Victor Frankenstein; also known as the world’s maddest scientist that has ever lived in the fictional world. As many people do not know, Mary Shelley subtitled her book â€Å"Or, The ModernRead MoreInsanity And The Insanity Defense1444 Words   |  6 Pagesbreakdown. There are two forms of an insanity defense, cognitive and volitional. In order for an individual to meet the requirements for cognitive insanity it must be proven that the defendant had to be so impaired by a mental disease at the time of the act that they did not know the nature of what they were doing. If they are fully aware of their actions, one must prove that they didn’t know what they were doing was wrong. Volitional insanity, also known as irresistible impulse, states that the defendantRead MoreThe Irish Potato Famine1505 Words   |  6 Pagesthe 1840s many Irish citizens lived in poverty. For food, the Irish relied almost entirely on potatoes because of their low cost and nutritional value. Then a devastating potato blight began in Europe in 1845 and destroyed the crops every year until 1851. Due to Ireland’s poor government the citizens we not able to recover from the famine quickly. Before the famine in the mid-1800s, â€Å"many English politicians and social reformers began to think that Ireland was a nation in need of transformation,Read MorePolitical System of Germany1700 Words   |  7 PagesGermany which will supersede state laws and have the same force as all other federal laws except the constitution. European Community law is directly binding within the Federal Republic of Germany without the necessity of further incorporation acts. The European Community institutions Decisions and Regulations are directly applicable (Heinz, 1992; 2-3). 3. History of criminal justice system. The Federal Republic of Germany was founded on May 23, 1949 with the declaration of the

The Death Of An Apartment Door Essay - 1235 Words

The escalating sounds of frenzied footsteps and shrieks had begun to frighten me, as I was walking to my friend’s home. Out of nowhere, my eyes started to burn and a hysterical cough overwhelmed my entire body. I had lost complete awareness of my surroundings. The oxygen fleeing my body with every cough left me in a state of terror. A faded figure wrapped their arm around me and assisted me into the lobby of an apartment building. As I partially regained my consciousness, an overlapping group of voices said,†Iyi misin?†, â€Å"Are you okay?† in Turkish. I nodded out of habit, although all I could think about was when my cough was going to cease. Forcing my eyelids fully open, I saw two distinct figures; a man with a torn piece of cloth wrapped around his head, whom I presumed helped get me off the street, and a concerned young woman awaiting outside an apartment door. A mid-aged woman rushed out of the apartment towards me, with her hands full. She leaned ov er my head and gently poured milk over my face, assuring me that I was going to feel better. I enjoyed the soothing sensation all over my face, though it was brief. Then, the woman begun squeezing lemon juice onto a white cloth, and told me to breathe into it. After a short while, my mind had been freed from captivity of the tear gas, and I came to an inspiring realization. These strangers had helped me without question. At the time, it did not matter to them who I was, where I was from or what beliefs I held. They most likelyShow MoreRelatedShort Story1666 Words   |  7 Pageshesitate. â€Å"Yep.† An hour later, Coates and Chay sat in their car in front of Shadontay Harris’ apartment when Chay got a call, he put the phone on speaker. Ricardo aka Rick Smith had been arrested for beating up the old woman he lived with. As soon as Chay disconnected the call, Coates spotted Shadontay got out of a car carrying a grocery bag. She tapped Chay and they watched as their suspect headed for his apartment. Coates raised an eyebrow. The boy is fine, Facebook didn’t do him justice. Chay noticedRead MoreThe Story Of My Life1723 Words   |  7 Pagesmoved out a year ago. My aunt helped out with my rent. She gotta it like that. You know, money, or else I would’ve had to put up with my mama. Savannah used to keep my mind off her, but now...† It was clear that he was shaken and hurt by Savannah’s death. He wanted to go into fashion and his mother used to criticize him for it, saying that only women and gay guys go into fashion. â€Å"I’m not gay, I just love fashion. I know people thought I had a crush on Savannah, but that was the farthest from the truthRead MoreAnother Cold Case for the FBI1342 Words   |  5 PagesGiselle Morales stood outside her boyfriends apartment, knocking on the door repeatedly. Joel! Joel! Open the door idiot! she screamed, in her deep Brooklyn accent, waking up all of the residents in his apartment building on the cold brisk New York morning. There was no response from the inside. She pulled her merm jacket around her, to protect herself from the December cold. The aroma of beef patties emerged from a nearby Caribbean restaurant. Giselle thought of knocking again, thenRead MoreThe Cask Of Amontillado By Edgar Allan Poe1588 Words   |  7 Pagesstories. Poe’s works mainly focused on horror and death. This could be due to the many deaths and hardships he has faced in his life time. Poe lived a short life of only forty years but works such as â€Å"The Cask of Amontillado†, The Murders in the Rue Morgue†, and â€Å"The Raven† made him a well-known writer. According to the Poe Museum he was seen as a morbid and mysterious man in the public eye thanks to Rufus Griswold who wrote Poe’s obituary after his death. In the â€Å"Cask of Amontillado† Poe focuses onRead MoreRear Window Comparison1118 Words   |  5 Pagesjewelry salesman, Lars Thorwald (Raymond Burr) who has a bedridden wife. Jeff’s girlfriend, Lisa Fremont (Grace Kelly), and his nurse, Stella (Thelma Ritter), visit him often. One night, Jeff hears a woman screaming and notices Thorwald leaving his apartment. The next morning, Thorwald cleans a handsaw and has men carry out a big trunk with rope wrapped around it. Jeff believes that Thorwald killed his wife and tells his friend Tom Doyle (Wendell Corey), a detective, and asks him to consider the situationRead MoreEssay about 12 Angery Men Moral Dilemma1046 Words   |  5 PagesTwelve Angry Men is a movie about a young boy on trial for murdering his father. If the boy is found guilty, he will be sentenced to death. The jury men are very aware of this fact, most are perfectly fine with sending this boy to die as one man searches for the empathy of his jury peers. One by one the jury begins to sway toward the not guilty plea, as every fact thrown into conversation gets disproved. Now, one lone juror faces not the pressure of his peers but the pressure of his emotional attachmentRead MoreAn Analysis Of Isaiah s The Night 802 Words   |  4 PagesIt was like the videos Isaiah watched online, but only ten times worse, and in person. People in the apartment started screaming. Isaiah heard the sound of footsteps, â€Å"thump, thump, thump.† People were probably running for their lives, and warning others to run for theirs. Isaiah opened his door and went to the lobby. He looked out the window, and saw the wave. It was coming closer to the apartment. Isaiah stood there traumatized. He snapped out it when a man yelled, â€Å"RUN!†. Isaiah hurried up theRead MorePersonal Narrative : The Happiest Day Of My Life1263 Words   |  6 PagesThe uproar of violent knocks on my front door and my front door unlocking permeated through the quiet s tudio apartment. My brain told me to run and hide, but my body stood rooted to the ground. I was frozen...except the one heavy warm tear trickling down what seemed like my lifeless face. It was exactly a month after my 12th birthday when my parents moved me and my younger siblings to VYV, an apartment building in Jersey City. For years before, I had begged my parents to let me babysit my siblingsRead MoreStephen R. Covey s Contents Of A Dead Man s Pockets1209 Words   |  5 Pagesimportance of enjoying life rather than chasing fruitless ambition through extensive symbolism and a touch of satire. At the beginning of the story, as main character Tom Benecke is organizing papers on his desk, he remarks on how hot it is in his apartment - showing that he feels stifled and uncomfortable where he is - and only then realizes that he is not hot, but feeling guilty. He is shown to be guilty because his wife, Clare, is going to the theatre by herself because Tom has chosen to stay andRead MoreAnalysis Of The Poem The Stone Of Laughter 1357 Words   |  6 Pagesbe. Khalil lives in an apartment building and he is neutral when it comes to the war, so he is typically inside, within the domestic sphere away from the violence and trauma. Being confined to his home, Khalil is somewhat protected from the dangers of the war. Even when the war intrudes on him and damages his apartment, like the typical societal woman that cleans up after the war, Khalil also senses the urge to clean up. Khalil occupies himself with cleaning his apartment after every war incident

Founding Fathers of the USA Essay Example For Students

Founding Fathers of the USA Essay There are many people who can be considered the indirectfounding fathers of The United States. Such people are TheChristian Crusaders, Marco Polo, Cortez, Pizarro, andMartin Luther. The Crusades were a series of holy warsfought to win the holy land of Christianity from those whofollow Mohammed. Even though these wars failed in therespect of winning the land back, they did triumph in anotheraspect. The crusaders introduced a lifestyle to the Europeansin the Holy Land that was more appealing than they knewbefore. Following the wars the Europeans returned and theycreated a market to deliver the desirable goods they cameaccustomed to in the Holy Land. This was one reason forthe beginning of exploration, and ultimately led to thediscovery of America. Marco Polo was a great explorer ofhis time. He wrote a manuscript on his voyage entitled, TheVoyage of Marco Polo. In this manuscript it said how theKahn of China lived in riches, used fine china, decoratedwith gold, and used spices. When the manuscript reachedthe people of Europe they realized how life could better ifthey had the materials as did the Khan. This discoveryencouraged people to find new places to find these riches. Cortez founded the city of Tenochtitlan, which was createdby the Aztecs in central Mexico. He said how the people ofthis town lived with the riches of a Khan. They city wasadvanced further than any European had seen in the NewWorld. The ruler of this land, Montezuma, lived in hugeroom filled with jewels, precious stones, silver, and anastonishing amount of gold. Soon after his arrival the Aztecsrebelled. Cortez had Indian and Spanish allies and won thebattle against the Aztecs. News of the conquest of Mexicocreated a rush of Spanish to America and led to furthersettling of the continent. Francisco Pizarro found the empireof the Incas in the Andes Mountains region. This empire, likethe Aztec Empire, was advanced and rich in gold and silver. Inca, the head of the Empire and was considered a God,was killed by Pizarro. This lessened the spirit of the Incasand made it easier for Pizarro and his men to succeed amongthem. This success, again, encouraged the Europeans tosettle their own area. One of the best known reformers,Martin Luther, can be considered a founding father of TheUnited States. Luther tried to reform the Church of England,and rid it of Catholic ways. He wrote his 95 Thesis thatattacked the ways of the church and helped to better it. Hisresentment of Rome and Catholicism helped to spread thereformation into Northern Europe. This in return created adream in adventurers like Columbus to look for a new routeto India in search for worthy goods. By avoiding Italy hediscovered America. Without Luthers ideas, Columbuswould never have the dream to find the route. Each of thesepeople can be considered the founding fathers of the UnitedStates. They all played an important role in history, and inthe making of the United S tate.

NAFTA and the Canadian Economy free essay sample

A detailed examination of the impact of the North American Free Trade Agreement (NAFTA) on the economy of Canada. This paper discusses the impact that NAFTA has had on the Canadian economy. Through examples of the role that NAFTA has played it is seen that this impact has been largely positive. Areas examined include NAFTAs role in mediating between the U.S. and Canada and increased employment through an increase in trade opportunity, among others. Arguments defending the role of NAFTA against criticism it has faced are also presented. Canada and the United States have had a long-standing friendship in which the two nations live peacefully side-by-side. The borders are not armed, the residents of each nation have respect for the other and there are many advantages enjoyed by remaining friendly. Just as any two friends will have disagreements from time to time, Canada and the US have also had their share of problems. We will write a custom essay sample on NAFTA and the Canadian Economy or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page One of the problems that has occurred from time to time between the two nations deals with the economics of each nation. NAFTA, which is a membership group designed to promote and improve trade relations within the member nations is sometimes called in to mediate between Canada and the US. NAFTA has had a positive impact on the Canadian economy overall, but it has not been without its problems for the northernmost country of the North American continent.

Internet Security Fraud essays

Internet Security Fraud essays The internet has played a major roll in the development of business and domestic industries. It is an everyday element in each and everyones lives. Through chat, surfing, shopping and banking. But society has now been confronted with the issue of security, primarily security in relation to internet banking. As most people know internet banking is a service provided which enables banking to take place in the comfort of our homes. It has revolutionised the way banking is performed. It is well noted that security is a number one priority in carrying out these objectives, as internet banking deals with a lot of financial information which if in the case where the information may escape, great consequences may result. This issue targets most of todays society as the majority engage in online transactions be it banking, chatting or shopping. The implementation of effective security measures provides users with peace of mind and a sense of trust in completing online transactions. To assist with this, the thorough education of users in the areas of security, risks and precautions in relation to the use of internet banking must be carried out to ensure that the most effective and safe procedure is being completed. The main target of online fraudsters is internet banking this issue will be discussed throughout the report. 2.1.1 Internet banking is an everyday bank with a virtual nature which is available to customers 24 hours 7 days a week. Internet banking provides services that banks offer such has the transfer of money from two separate accounts, viewing of account balances and other transactions in the comfort of your home. Internet banking is provided by the majority of major banks in the form of a webpage which lists users accounts and provides a vast variety of options and actions to be carried out while being secure. All customers of major ban ...

How Bureaucracy stands in the way Essay Example | Topics and Well Written Essays - 250 words

How Bureaucracy stands in the way - Essay Example Teachers have limited access to technology, instructional resources, materials which aid them in teaching the students. Teaching curriculums in schools remain not fit for the students because teachers don’t have access to engaging curriculums which reaches the international academic requirements (The Broad Foundation, 2013). Inadequate students’ mentors and master teachers also contribute to failure of education. Teachers are not free to reach their heads as well as the students due to bureaucracy. Less attention to students’ needs and complaints is also very common in many schools. The school committee focuses mostly on time spending meetings, struggle for leadership and setting of policies benefiting themselves. In all these undertakings what is affecting the teachers and students is never discussed therefore the low academic achievements. The labor laws and agreements prevent the board members from directly communicating to teachers and students and therefore their problems are never addressed on. In the school systems, the issue of accountability brings a lot of problems as there is conflict of who is responsible of this or that (The Broad Foundation,

Effect of Videogames on health and socially Essay

Effect of Videogames on health and socially - Essay Example In any case, it is impossible to isolate videogames completely from human life in this era of advanced science and technology. This paper analyses how videogames affect the human health and the society. According to Anderson (2003), videogames are an excellent tool for teachers to stimulate learning among the students. At the same time, violent video games have the potential to cause immense social problems. Videogames are a double edged sword. Teachers can teach difficult lessons with the help of videogames so that the students get more insights about difficult topics. For example, while teaching subjects such as physics and chemistry, teachers can make use of videogames. Imagine a case in which a teacher is teaching missile technology in a physics class. There are plenty of videogames available in the market in which fight using missiles or guns is the major theme. Such videogames can be used effectively by a teacher to teach the topics related to the operations of a missile. In short, videogames have the potential to cultivate positive effects in a society since it has the ability to stimulate or enhance the learning process. Kim et al (2010) pointed that â€Å"excessive playing of video games may result in impaired academic performance. Videogames have the ability to cultivate a kind of addiction among teenagers. Majority of the videogames are organized in such a way that each player should cross many difficult levels before reaching the target. When a teenager fails to overcome a particular difficulty level, he may spend more and more time in front of the computers or mobile phones for solving the puzzles created by the videogames. Thus he may not get enough time to spend for academic studies. Thus his studies can be negatively influenced by the addiction generated towards videogames. Teachers and parents are of the view that children who spent more time for playing videogames may spent little time for doing their home works, assignments or

Role of the Genes COLEC11 and MASP1 in Embryonic Development

Role of the Genes COLEC11 and MASP1 in Embryonic Development Vigneshwaree Sabapathy Mutations in the genes COLEC11 and MASP1 which code for lectin complement pathway proteins have been found responsible for a rare autosomal recessive disorder resulting in abnormal development. This proposes that other constituent proteins may play a role in embryonic development. To this day, the genetic aspects of the stages involved in embryonic development that leads to certain congenital disorders are still not fully understood. As a result, researchers start off with identifying the genes that play a part in causing a congenital disorder before determining how these genes bring about the disorder. This approach was adopted by Rooryck et al.1 to help prove that mutations in the genes COLEC11 and MASP1, involved in the lectin complement pathway were responsible for 3MC syndrome. The 3MC syndrome is an abbreviation of Michels, Mingarelli, Malpuech and Carnevale syndrome. These four syndromes are rare autosomal disorder that follows a recessive order of inheritance. The 3MC syndrome is characterised by blepharophimosis, ptosis of the eyelids, cleft lip and palate, craniosynostosis, hypertelorism and in some cases renal anomalies and umbilical hernia1,2. Furthermore, growth retardation, mental retardation and urogenital anomalies are also common features in all four syndromes2,3. After much research, it was found that the overlapping similarities in phenotype and Gestalt between these four syndromes are more significant than the differences between them2. Therefore, these evidence lead to the assumption that the syndromes are allelic variations of one another and belong to the same spectrum2. Rooryck and colleagues started off their study by first collecting DNA samples from individuals diagnosed with Michels, Mingarelli, Malpuech and Carnevale syndromes and all their available family members. Their genomes were then screened for single nucleotide polymorphisms which are homozygous in all affected individuals but absent in unaffected individuals. From the individuals tested, there were four consanguineous families. The genotyping results from members of these families showed a homozygous region of 2.2 MB at 2p25.3 in affected individuals1. Moreover, a region of homozygosity was found in two other families at 3q27.31,4. These findings suggest that the 3MC syndrome could be caused by multiple genes. From the sequencing of the open reading frames at the 2p25.3 region, 15 candidate genes were found, of which 9 were sequenced. Sequencing of these transcripts in affected individuals revealed three homozygous missense mutations and a single base deletion in COLEC11 that may be linked to the inheritance of the 3MC syndrome. Furthermore, the single base deletion in COLEC11 was found to play a role in the premature termination of the gene product CL-K1. CL-K1 is a C-type lectin that acts as a host defence by binding to carbohydrate antigens on microorganisms and activating the innate immune system5,6. Due to its function, it tends to circulate in the serum. In addition, being highly conserved in various species means that a mutation would be damaging to the function of the protein. Hence, to ensure that this mutation is an underlying cause of the 3MC syndrome, a protein blot assay was conducted to detect CL-K1 in the serum from two affected individuals. However, none was detected, indic ating a connection between the syndrome and the loss of function mutation in COLEC11. At the same time, the expression of CL-K1 was observed in certain mouse tissues that have been known to be affected by the disorder in humans1. In the same way, sequencing at the 3q27.3 region found 16 candidate genes potentially linked to the 3MC syndrome. One of these genes is the MASP1 gene which encodes for mannan-binding lectin serine protease 1 (MASP-1), a serine protease that is important in the lectin complement pathway4. Rooryck et al.1 then sequenced this gene in the two affected families and discovered two homozygous single base substitutions in exon 12. As predicted, the loss of function of this gene is consistent with the inheritance of 3MC syndrome. To study the effect of the loss-of-function of these proteins as well as to ensure that both the COLEC11 and MASP1 genes are accountable for the abnormalities witnessed in 3MC syndrome, knockdown studies were conducted using zebrafish. In these studies, two antisense morpholinos for COLEC11 were injected into one-cell stage embryos of zebrafish so as to imitate the loss-of-function of the gene. The same was done for the MASP1 gene. Based on the results from these studies, COLEC11 and MASP1 genes were found to cause similar phenotypes. The zebrafish morphants subjected to both these treatments displayed morphological abnormalities such as pigmentation and craniofacial cartilage defect similar to the symptoms of 3MC syndrome. Interestingly, when co-injected with a fully functional COLEC11 mRNA, the observed abnormalities in the zebrafish are reversed. Additionally, injecting a low dosage of both colec11 and masp1 morpholinos into the zebrafish embryos at the same time gave rise to simi lar deformities observed when injected separately, suggesting an interaction between the two genes5. Thanks to the pigmentation and craniofacial cartilage defects noted in zebrafish morphants, further studies were carried out to determine whether the CL-K1 and MASP-1 proteins are involved in the migration of cranial neural crest cells (NCCs) during embryonic development. Findings by Rooryck et al.1 in this part of the study revealed that beads coated with CL-K1 attracted NCCs when placed in the head region of zebrafish embryo. On the other hand, control beads implanted in the same region did not display the same attraction to NCCs. This proves the possibility that CL-K1 play a role in guiding the migration of neural crest cells. Similar results were also seen in a test using CL-K1 agarose disk and HeLa cells. At present, since the roles of both the COLEC11 and MASP1 genes in embryonic development have been discovered, more focus is required in investigating how the lectin complement pathway regulates embryonic development in addition to the role of the gene product, CL-K1 in early developmental processes. Likewise, the possibility of other constituent proteins and complement systems being involved in embryogenesis should also be considered. Therefore, further research on these aspects can help in the management of other congenital genetic disorders. (996 words) References: Rooryck, C. et al. Mutations in lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndrome. Nat. Genet. 43, 197-203 (2011). Titomanlio, L. et al. Michels Syndrome, Carnevale Syndrome, OSA Syndrome, and Malpuech Syndrome: Variable Expression of a Single Disorder (3MC Syndrome)? Am. J. Med. Genet. 137A, 332–335 (2005). Kerstjens-Frederikse, W.S., Brunner, H.G., van Dael, C.M.L. van Essen, A.J. Malpuech Syndrome: Three Patients and a Review. Am. J. Med. Genet. 134A, 450–453 (2005). Sirmaci et al. MASP1 Mutations in Patients with Facial, Umbilical, Coccygeal, and Auditory Findings of Carnevale, Malpuech, OSA, and Michels Syndromes. Am. J. Human Genet. 87, 679–686 (2010). Hansen, S. et al. Collectin 11 (CL-11, CL-K1) Is a MASP-1/3–Associated Plasma Collectin with Microbial-Binding Activity. J. Immunol. 185, 6096–6104 (2010). Keshi, H et al. Identification and characterization of a novel human collectin CL-K1. Microbiol Immunol. 50, 1001-1013 (2006).

The Yalta Conference :: essays research papers

The Yalta Conference was one of the most important events in history, let alone, this century. It took place from February 4 to February 11, 1945, at Yalta, Crimea, a port/resort. The three main individuals at this meeting were Churchill of Great Britain, Roosevelt of the United States and Stalin of the U.S.S.R, known back then, and now known as Russia. This meeting was to discuss the post war effects. The publics opinion of this was of a great Anglo-American- Soviet friendship. The agreement that as achieved at the conference was that a Coalition government would be set up in Poland. This guaranteed free election in Poland. It also gave eastern Poland to the Soviet Union and in return, Poland would receive land from Germany. Germany on the other hand was divided into four zones which were Great Britain, United States, France, and the Soviet Union. Germany had to pay all reparations of the war but not to the extent of World War I. One other major decision made in the conference was the creation of the United Nations. This was a new world organization which worked for world peace as did the League of Nations. Along with the Soviet Union, Byelorussia and the Ukraine were admitted into the United Nations. Since Russia had influence on there voting, the United States was given 3 votes to be equal with the Soviet Union. After the conference, American public opinion was very high and all of the Allied nations responded favorably. There were also secret agreements that were made but kept secret until the end of the war. It was said that the Soviet Union were to enter the war against Japan two to three months after the end of the war in Europe. This was necessary in order for The Soviet Union to regroup because of the heavy causalities in Europe. The Soviet Union had a great advantage in the secret agreement. It received much land and did not have to do much in the end for it because of the use of the atomic bomb which ended the war much earlier then expected and the Soviet Union did not even have to fight Japan. In the classroom simulation of the Yalta Conference, the same results were not reached. The Soviet Union was not able to get most of its demands because in the classroom, most of the student looked at communism was not looked at very favorably.

Colonialism and the Struggles of the Black Psyche Essay

The book â€Å"Black Skin, White Masks† by Frantz Fanon analyzes the psychological damage that colonialism wrought on the colonizer and the colonized. Fanon also bases his analyses on his own experiences, wherein he describes how black children develop neuroses that root from their antagonism of their own skin, because of the media and their daily circumstances: â€Å"The dominant colonial culture†¦identifies the black skin of the Negro with impurity; and the Antilleans accept this association and so come to despise themselves† (Appiah ix). The source of â€Å"Black Skin, White Masks† is the psychological injury from colonialism, racism, and gender inequality, an injury that will escape recovery, unless the black psyche conquers its inner white demons and alienate all that alienates him/her. Fanon writes from the experiences and psychiatric analyses of the black skin and the white masks that black people don. He describes a girl who is afraid of black people: â€Å"†¦it is at this age that the Negro as savage and cannibal makes his appearance. It is easy to make the connection† (Fanon 184). This fear for the black skin is also emphasized and criticized in the painting â€Å"How Do You Like Me Now† (1988) (fig. 1) by David Hammons. This fourteen-by-sixteen-foot painting shows political leader Jesse Jackson with blond, wavy hair, blue eyes, pink cheeks, and white skin. The title is also a song of a popular rapper Kool Moe Dee. This painting can be interpreted from different perspectives. Barnwell and Buick argue that white viewers can see the painting from their perspective, wherein they are challenged to see through their biases and consider voting for a black man, now that he is â€Å"whitened. At the same time, the painting â€Å"asks black viewers whether they would support Jackson if he were white,† say Barnwell and Buick. On the other hand, the interpretation of the paintings also changes with the race of the artist. Barnwell and Buick explore the changes in meanings of the artwork, if Hammons race is changed from black to white. This painting has bee n attacked ten black men, who thought that it was racist and insulting, and they used sledgehammers to assail it and take it away from its scaffolding. Barnwell and Buick wonder if the black group would have still destroyed the painting, if they knew that the painter was black and that he was merely satirizing the color lines that enslave people’s minds. Clearly, blackness and whiteness release the innermost values and emotions of the people. The reactions can reflect the anger and despondency of the subjugated black race. â€Å"How Do You Like Me Now† (1988), as seen by the violent response of some people, has clearly marred the colonized. Colonialism has injured the black psyche to the extent that violence has been etched into it too. Colonialism has stripped black people of the right to define their identities, by caricaturing their existence and purpose in life. Colonialism, like slavery, skews the black people’s right to humanity and power. Violence, however, can regain this loss of power and replace the sense of loss. Through violence, the gap between power and powerlessness can be filled again. â€Å"How Do You Like Me Now† (1988) also remarks on the damage of colonization and racism to the colonizer. From the racist white perspective, this blonde man is a person who has greater potential for being a president. If faced with a black person, with black eyes and curly hair, the racist white would be offended with the overarching blackness. It will feel, like Fanon’s little girl who is afraid of black people, that they are being assaulted. The size of the painting also asserts power. But since colonial and white America would not consider any immense power from the black people, it is important to wear the white mask. With the black person masked as white, he will be accepted and he will have power. This is the same critique of Fanon of colonizers. The colonizers have forgotten that the black people also have their own identities. The whites see no black individuality and power, but only their whiteness. This seeing of whiteness on blackness marks another neurosis from the side of the whites. What is it about their whiteness that they have loved themselves too deeply and too irrationally? Following the analysis of Fanon, having power and asking for too much of it dehumanized the white race of the colonial times. That power is white has been embedded in their mind, an embedding that has been too violently engraved that to remove it also means to aggressively remove a part of them. Thus, the colonized is psychologically damaged too. But as the black people who hammered away â€Å"How Do You Like Me Now† (1988) showed, it is not acceptable to be a non-human being. It is not acceptable to be colonized and still feel like a normal human being. There must be catharsis. There must be freedom from all alienations. The painting â€Å"Wives of Shango† (n. d. ) (fig. 2) by Jeff Donaldson captures the liberation from three fronts- liberation of race, liberation of gender, and liberation from one’s own struggles. In this painting, three black women are adorned with bullets and money. The two are not looking back at the viewers, but have superiority in the way their chins are turned up. The middle woman at the back dares to look back at the viewers. But the expression is fierce, and it makes viewers look away. This painting is an image of power. This image breaks away the â€Å"comparaison† that Fanon talks about. Fanon argues that blacks are in the state of â€Å"comparaison,† wherein: â€Å"†¦he is constantly preoccupied with self-assertion and the ego ideal† (185-186). This preoccupation is about blacks being â€Å"always dependent on the presence of ‘The Other’† (Fanon 186). â€Å"Wives of Shango† (n. d. ) is interpreted as the shedding away of this â€Å"comparaison. It does not have a drop of submission or weakness. The women symbolize the power of their gender and race. They are willing to pay and kill to exert power. They are willing to dominate their personal struggles too, by fixing it through money and blood. But the means of money and violence, on the other hand, can also be interpreted as the product of the white gaze. Is it possible that these women are also still being white, by using the same arsenals of the white race? The white race entered and conquered through violence and money. Are the black people going to fight back with the same kind of brutal force? In doing so, they are â€Å"being white† too. Fanon argues that to be black, black people should also accept their whiteness. Fanon says: â€Å"I am French† (179), which includes being part of the white French culture. Fanon argues that the black people could not annihilate the whiteness in them. In the same way, white people can also not demolish the blackness inside them. White and black have mixed already, and this merging of two races and cultures cannot be ignored. Though the white demon has seeded inferiority complex in the black psyche, Fanon suggests that the way to recovery from the white’s subjugation is accepting â€Å"that which is white† in them. The alienation that black people feel is another problem, as it has divided the black psyche into numerous conflicting dimensions. Fanon says: â€Å"That this self-division is a direct result of colonialist subjugation is beyond question† (17). The alienation renders unspeakable psychiatric damages as it injects â€Å"compound, ambiguous, and unsettling results, both internally and externally† (Brown-Guillory 35). Fanon recommends a white mask, but not all people can wear it. â€Å"Wives of Shango† (n. d. ) detaches itself from the white mask. It stresses the power of the black psyche that can be hung outside in full glory. This black psyche might be afraid though, even when it is confident. The women wear symbols of violence and fighting. They know that re-locating their positions in power centers can have drawbacks, and they are prepared with ammunition. Alienation has corrupted the mind completely that fear has been entrenched in the actions and beliefs of the black people. This is where Fanon makes sense. Fear that alienation has created can only be undone through accepting the whiteness. It is also about mending the anger with peace, not with violence. The white mask does not represent another form of oppression. It symbolizes the feeling of safety and trust with whiteness. It signifies the end of domination of the black, because anytime, that mask can be removed. And fundamentally, it is still a white mask. Fanon makes several strong points. Racism, colonialism, and sexism have maimed the psyche of the white and black people. They are divided within, because of these oppressive experiences. But the blacks can recover from this damage, as long as they can handle wearing the white mask. At the same time, they must remember that the white mask is only a mask. It is important for the black people to also find their black identities and revel in the dignity of wearing it inside and out.

Gandhi Heros Journey Essay - 936 Words

Mahatma Gandhi once said, â€Å"You must be the change you wish to see in the world†. This shows that Gandhi believed in peaceful change. Gandhi was well known in India by many people. People were inspired by his ways and would stand by him in peaceful protesting. A lot of people believed in Gandhi as a hero. Just as well, Percy Jackson from the Lightning Thief is a known hero for stopping world WWIII between the gods. Both Gandhi and Percy Jackson follow the path of the hero s journey because they re both trying to complete a task. Mahatma Gandhi is a religious Indian who wanted independence from the British for his people. He wanted to do this in a peaceful way because he did not want violence. Mahatma Gandhi was called to adventure when†¦show more content†¦Percy is a hero because he saved the world of WWIII of the gods. In chapter 9 Percy starts his path on the hero s journey when he is called to complete a quest. The conversation is between the centaur Chiron and Percy. Your quest, of course. Will you accept it? I glanced at Grover, who was crossing his fingers. Um, sir, I said, you haven t told me what it is yet. Chiron grimaced. Well, that s the hard part, the details.Thunder rumbled across the valley. The storm clouds had now reached the edge of the beach. As far as I could see, the sky and the sea were boiling together.Poseidon and Zeus, I said. They re fighting over something valuable ... something that was stolen, aren t they? This shows that Percy was just called to adventure. Percy was ju st given a task to stop a war between the gods. This shows that Percy just stepped foot on the hero s journey since this was his call to adventure. â€Å"Percy starts his journey on the road of trials when HE ENCOUNTERS THE FURIES, WHO ARE HADES HELPERS. The text says â€Å"Annabeth and Grover moved up behind the Furies cautiously, looking for an opening. I took the ballpoint pen out of my pocket and uncapped it. Riptide elongated into a shimmering double-edged sword. The Furies hesitated. Mrs. Dodds had felt Riptide’s blade before. She obviously didn’t like seeing it again. â€Å"Submit now,† she hissed.Show MoreRelatedComparing the Journeys of Hesses Siddhartha and Gandhi Essay2049 Words   |  9 Pages      Ã‚  Ã‚  Ã‚   Siddhartha and Gandhi strove for different goals during their lives. Siddharthas goal was very personal, while Gandhis goal encompassed the world. This was shown by their spiritual development throughout their journeys. Siddhartha evolved from an inexperienced spiritual being to a man, returned to spirituality, and ended with nirvana. Gandhi traveled a much straighter path, originally being a worldly man merely seeking his correct place in life, when his spiritual development unexpectedly